Alex Castellarnau Selected Research

astodrimer

1/2022	Astodrimer sodium antiviral nasal spray for reducing respiratory infections is safe and well tolerated in a randomized controlled trial.
4/2021	A phase 3, randomized, controlled trial of Astodrimer 1% Gel for preventing recurrent bacterial vaginosis.
1/2021	Virucidal and antiviral activity of astodrimer sodium against SARS-CoV-2 in vitro.
1/2021	Protective Effects of Astodrimer Sodium 1% Nasal Spray Formulation against SARS-CoV-2 Nasal Challenge in K18-hACE2 Mice.
2/2020	Two phase 3, double-blind, placebo-controlled studies of the efficacy and safety of Astodrimer 1% Gel for the treatment of bacterial vaginosis.
1/2020	A phase 2, double-blind, multicenter, randomized, placebo-controlled, dose‑ranging study of the efficacy and safety of Astodrimer Gel for the treatment of bacterial vaginosis.

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Alex Castellarnau Research Topics

Disease

3	Infections 01/2022 - 01/2021
3	Vaginal Discharge 04/2021 - 01/2020
3	Bacterial Vaginosis 04/2021 - 01/2020
2	Vulvovaginal Candidiasis 04/2021 - 02/2020
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2022
1	Virus Diseases (Viral Diseases) 01/2022
1	Urinary Tract Infections (Urinary Tract Infection) 04/2021

Drug/Important Bio-Agent (IBA)

6	astodrimerIBA 01/2022 - 01/2020
2	Dendrimers (Dendrons)IBA 02/2020 - 01/2020
1	Nasal SpraysIBA 01/2022
1	Antiviral Agents (Antivirals)IBA 01/2022
1	Metronidazole (Metric)FDA LinkGeneric 04/2021
1	Vaginal Creams, Foams, and Jellies (Vaginal Tablet)IBA 02/2020
1	CelluloseIBA 01/2020

Therapy/Procedure

1	Intranasal Administration 01/2022
1	Aftercare (After-Treatment) 01/2021